Using Plasma for Surface Treatment and Decontamination
Plasma: A safer and greener solution for life science
Plasma is a clean and cost-effective way of sterilization, bonding enhancement, and increased wettability for life science research. Plasma generation doesn’t require hazardous chemicals so it’s a clean and hazard-free process that often yields superior results to traditional surface preparation techniques.
Plasma Surface Treatment Of Biomaterials
Acceleration of research and discovery in the biological science areas rely on advancing technologies in regenerative medicine, cellular, and bio-molecular isolation.
Products and platforms such as tissue scaffolds, immunoassays, cell culture media, filtration and analyte delivery devices require plasma surface modification to enable selective bio-molecular immobilization and to avoid surface effects due to miniaturization.
Newly developed micro-fluidic platforms used throughout multiple industries including the life
science fields of drug discovery, diagnostics, medical device and drug delivery are significantly enhanced with plasma treatment. Micro-channels on clinical diagnostic devices are made “wettable” to fluids improving both flow and dispensing.
Surfaces that come in contact with biological environments
such as the human body can be engineered
to elicit specific biological responses, e.g.
anti-fouling, anti-microbial, anti-thrombogenic etc.
This can be achieved by direct use of plasma produced
surfaces. Alternately plasma can be used to
tailor surface chemistries with specific functional
groups to act as a defined bio-molecule tie layer.
- Addition of monolayer precursors can ensure binding of specific functional groups
- Hydrophobic, hydrophilic, and super-hydrophobic surface characteristics can be engineered to experiment needs
- Chemical cleaning can leave behind dangerous contaminants which can have harmful side effects on cell cultures and chemical reactions. Plasma eliminates the need for solvents and creates a much cleaner surface for experimentation.
- Plasma-assisted quartz-like coatings reduce leeching effects by up to 90% over traditional methods
- Cleans surfaces of protein, chemical, and cell contamination
- Reduces carbon residues left by standard cleaning and polishing methods
- Decrease in contamination and residues promote better adhesion
- Increases wettability, adherance, and cohesion in immunoassays, cell cultures, and microarrays
- Prevents overflowing and cross-contamination
- Promotes antigen binding
- Increases binding selectivity
Cleaning and Sterilization