Life Science

Using Plasma for Surface Treatment and DecontaminationPlasma: A Safer and Greener solution

Plasma: A safer and greener solution for life science

Plasma is a clean and cost-effective way of sterilization, bonding enhancement, and increased wettability for life science research. Plasma generation doesn’t require hazardous chemicals so it’s a clean and hazard-free process that often yields superior results to traditional surface preparation techniques.

Plasma Surface Treatment Of Biomaterials

Acceleration of research and discovery in the biological science areas rely on advancing technologies in regenerative medicine, cellular, and bio-molecular isolation.
Products and platforms such as tissue scaffolds, immunoassays, cell culture media, filtration and analyte delivery devices require plasma surface modification to enable selective bio-molecular immobilization and to avoid surface effects due to miniaturization.
Newly developed micro-fluidic platforms used throughout multiple industries including the life
science fields of drug discovery, diagnostics, medical device and drug delivery are significantly enhanced with plasma treatment. Micro-channels on clinical diagnostic devices are made “wettable” to fluids improving both flow and dispensing.

Medical Devices

Surfaces that come in contact with biological environments
such as the human body can be engineered
to elicit specific biological responses, e.g.
anti-fouling, anti-microbial, anti-thrombogenic etc.
This can be achieved by direct use of plasma produced
surfaces. Alternately plasma can be used to
tailor surface chemistries with specific functional
groups to act as a defined bio-molecule tie layer.

Applications

Precursor Enhancement
Precursor Enhancement
  • Addition of monolayer precursors can ensure binding of specific functional groups
  • Hydrophobic, hydrophilic, and super-hydrophobic surface characteristics can be engineered to experiment needs
Reduction of Surface Contaminants
Reduce Surface Contaminants
  • Chemical cleaning can leave behind dangerous contaminants which can have harmful side effects on cell cultures and chemical reactions. Plasma eliminates the need for solvents and creates a much cleaner surface for experimentation.
  • Plasma-assisted quartz-like coatings reduce leeching effects by up to 90% over traditional methods

 

Sterilization / Decontamination
Sterilization / Decontamination
  • Cleans surfaces of protein, chemical, and cell contamination
  • Reduces carbon residues left by standard cleaning and polishing methods
  • Decrease in contamination and residues promote better adhesion
Functionalizing Surfaces
Functionalizing Surfaces
  • Increases wettability, adherance, and cohesion in immunoassays, cell cultures, and microarrays
  • Prevents overflowing and cross-contamination
  • Promotes antigen binding
  • Increases binding selectivity

Application Notes

Cleaning and Sterilization 

• GlassCleaning • IOL Depyrogenation • Orthopedics • Spinal Implants

Coatings

Catheters • DNA and Protein • Microarrays • Low Cell Attachment  • Hydrophobic Surfaces   • PTFE • OLs • Contact Lenses

Precursor Enhancement

Principals of ALD Surface Engineering • SurfaceModificationDial